KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
11.82
Human Site:
S712
Identified Species:
20
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S712
F
L
V
D
A
V
T
S
S
G
P
I
L
A
E
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S712
F
L
V
D
A
V
T
S
S
G
P
T
L
A
E
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
S706
L
V
D
A
V
T
S
S
A
P
T
L
A
E
E
Dog
Lupus familis
XP_532028
914
101864
A800
L
L
M
D
F
T
E
A
T
P
L
A
E
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S711
L
V
D
A
V
T
S
S
A
P
P
L
P
E
D
Rat
Rattus norvegicus
Q5FVG2
731
81700
S711
L
V
D
A
V
T
S
S
A
P
P
L
P
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
R712
F
S
V
D
A
V
T
R
P
L
C
F
S
M
L
Chicken
Gallus gallus
XP_422083
502
57358
A484
H
E
R
N
A
K
N
A
G
M
H
S
G
A
V
Frog
Xenopus laevis
NP_001080234
498
57093
A480
H
E
Q
N
A
K
N
A
G
K
A
M
E
L
R
Zebra Danio
Brachydanio rerio
O57457
619
70690
R601
A
P
T
A
R
T
E
R
G
L
C
C
P
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
L889
T
L
S
E
Q
E
R
L
E
S
Q
K
T
N
Q
Honey Bee
Apis mellifera
XP_623974
809
90976
Q791
P
Q
T
T
T
T
D
Q
T
P
I
K
H
T
V
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
M913
E
E
R
R
V
T
Q
M
Q
Y
I
A
W
P
D
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
T714
P
A
A
P
A
V
A
T
S
A
C
G
L
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
93.3
13.3
13.3
N.A.
13.3
13.3
N.A.
40
13.3
6.6
0
N.A.
6.6
0
0
26.6
P-Site Similarity:
100
93.3
40
33.3
N.A.
46.6
46.6
N.A.
40
26.6
26.6
0
N.A.
20
6.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
29
43
0
8
22
22
8
8
15
8
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
22
8
0
0
0
% C
% Asp:
0
0
22
29
0
0
8
0
0
0
0
0
0
0
22
% D
% Glu:
8
22
0
8
0
8
15
0
8
0
0
0
15
15
22
% E
% Phe:
22
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
22
15
0
8
8
8
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
8
0
0
8
% I
% Lys:
0
0
0
0
0
15
0
0
0
8
0
15
0
8
0
% K
% Leu:
29
29
0
0
0
0
0
8
0
15
8
22
22
8
8
% L
% Met:
0
0
8
0
0
0
0
8
0
8
0
8
0
8
0
% M
% Asn:
0
0
0
15
0
0
15
0
0
0
0
0
0
8
0
% N
% Pro:
15
8
0
8
0
0
0
0
8
36
29
0
22
22
0
% P
% Gln:
0
8
8
0
8
0
8
8
8
0
8
0
0
0
8
% Q
% Arg:
0
0
15
8
8
0
8
15
0
0
0
0
0
0
8
% R
% Ser:
0
8
8
0
0
0
22
36
22
8
0
8
8
0
8
% S
% Thr:
8
0
15
8
8
50
22
8
15
0
8
8
8
8
0
% T
% Val:
0
22
22
0
29
29
0
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _